Parkinson Disease Risk Increased in Bipolar Disorder

Individuals with bipolar disorder (BD) have a higher incidence of Parkinson disease (PD), according to the results of a study published in Neurology. In addition, more frequent manic/mixed and depressive episodes increase this risk...

The study found that those with BD had a higher incidence of PD and a shorter duration from enrollment to diagnosis of PD than control individuals during the follow-up period (0.7% vs 0.1%). Patients with a higher frequency of psychiatric admission for BD had an increased risk of developing PD compared with those admitted less than once per year. The hazard ratio for developing PD for 1 to 2 manic/mixed episodes per year was 4.02, whereas for 1 to 2 depressive episodes per year, it was 2.67. For more than 2 episodes per year, the hazard ratios were 6.29 for manic/mixed and 6.19 for depressive.

Read the entire article from Psychiatry Advisor here.